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Turbo-Documentation

Hosts the Github Pages site documenting the UPenn Biobank TURBO project

TURBO

Transforming and Unifying Research with Biomedical Ontologies.

The goal of the PennTURBO project is to accelerate finding and connecting key information from clinical records for research through semantic associations to the processes that generated the clinical data. Discovery of previously unappreciated relations between the data are made possible by these associations. The PennTURBO Group will be applying ontologies primarily from the Open Biological and Biomedical Ontologies (OBO) Foundry obofoundry.org to provide a common semantic framework for Penn data. Transforming clinical data in this way allows the group to use graph database technologies for navigating the highly heterogeneous data.

Ontology

The TURBO group has developed an application ontology, TURBO ontology, that is based on the Ontology for Biobanking and uses OBO Foundry terms wherever possible.

Technology

The TURBO group has developed a technology stack that implements a pipeline to transform tabular data into semantic triples, stored in a Resource Description Framework (RDF) triple store, using terms from the TURBO Ontology.

Overview of steps in TURBO

TURBO overview image

  1. Export the relational data to .csv files.
  2. Map the relational data files to the TURBO ontology using Karma.
  3. Use the Drivetrain application to import the data into a GraphDB instance.